Real Betis vs Atlético Madrid – Can Home Advantage Decide this Copa del Rey Clash?

In a highly anticipated 2026 Copa del Rey quarter-final that pits Andalusian grit against Madrid’s pedigree, Real Betis vs Atlético Madrid headlines the cup action on Thursday, February 5, 2026, as Los Verdiblancos host Los Colchoneros at Estadio La Cartuja de Sevilla.

Real Betis, who advanced with a convincing 3-0 win over Cádiz in the round of 16, sit 8th in La Liga but face a stern test against Atlético, who cruised past Real Sociedad 4-1 in their last cup outing.

Diego Simeone’s Atleti, third in 2025-26 La Liga, boast a formidable cup record (unbeaten in 10 straight Copa matches), but injuries to key players like Robin Le Normand could hinder their quest for a first Copa title since 2013.

With Betis unbeaten in their last five home cup matches and Atlético boasting four wins in their last five on the road, this Real Betis vs Atlético Madrid clash is set to deliver plenty of intensity and maybe even some extra-time drama in Seville.

Real Betis vs Atlético Madrid – Date, Time, Predictions, and More

Match	Real Betis vs Atlético Madrid
Competition	Copa del Rey – Knockout Round (quarter-final)
Date	Thursday, February 5, 2026
Kick-off Time	9:00 PM CET (3:00 PM ET / 12:00 PM PT)
Venue	Estadio de La Cartuja, Seville
Copa del Rey form	Real Betis: WWWW Atletico Madrid: WW

USA, Canada, and Australian fans, it’s afternoon viewing—perfect for cup drama.

Team News and Analysis

Real Betis Team News

Betis are expected to have most of their regular starters available. Rotation is possible, but the manager is likely to name a strong XI given the importance of the tie. Betis will look to protect midfield balance while committing enough bodies forward, especially through the wide areas.

Atlético Madrid Team News

Atlético may rotate selectively, but should still field a competitive lineup. Simeone typically prioritises defensive solidity in away cup ties, with experienced leaders anchoring the back line and quick forwards ready to exploit space on the counter.

Head-to-Head Record

Atlético leads the head-to-head with 25 wins from 52 matches, compared to Betis’s 15, along with 12 draws.

The Colchoneros have taken 3 of the last 5 meetings, but Betis are unbeaten in their last 2 home games against them. Matches average 2.6 goals, with over 2.5 goals in 55% of them.

All-time H2H

Date	Competition	Result	Score
Oct 27, 2025	La Liga	Real Betis 1-0 Atlético Madrid	1-0
Aug 3, 2025	La Liga	Atlético Madrid 2-0 Real Betis	2-0
Mar 3, 2025	La Liga	Real Betis 2-1 Atlético Madrid	2-1
Oct 22, 2024	La Liga	Atlético Madrid 0-0 Real Betis	0-0
Apr 2, 2024	La Liga	Real Betis 2-1 Atlético Madrid	2-1

La Cartuja: Mixed, but Betis strong in recent home.

Real Betis vs Atlético Madrid Predicted XI Lineups

Real Betis Possible Starting Lineup: Adrian; Ruibal, Diego Llorente, Bartra, Rodriguez; Altimira, Roca; Antony, Deossa, Ezzalzouli; Avila
Atletico Madrid Possible Starting Lineup: Musso; Ruggeri, Hancko, Pubill, Molina; Baena, Cardoso, Llorente, Simeone; Alvarez, Almada

Pellegrini/Simeone briefings: Betis Fornals behind Bakambu; Atlético Álvarez partner Sorloth. Subs: Vitor Roque (Betis), Griezmann (Atlético).

Key Players

Real Betis: Pablo Fornals – Midfielder’s creativity (assists/key passes) orchestrates; vision unlocks Atlético’s defense.
Atlético Madrid: Julián Álvarez – Forward’s finishing (9 goals) punishes errors; movement tests Betis’s backline.

Tactical Outlook

Betis will aim to control possession and stretch Atlético laterally, using overlaps and quick combinations around the box.

Atlético are likely to sit deeper, deny central spaces and rely on fast transitions and set pieces. The first goal could completely change the game’s rhythm.

Match Prediction

Atlético’s form and Álvarez’s edge overpower Betis’s home resolve in a tense Copa del Rey quarter-final, securing a narrow win via second-half quality. Verdiblancos rally but falter.